Human Cancer Biology The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research

نویسندگان

  • Martin A. Cheever
  • James P. Allison
  • Andrea S. Ferris
  • Olivera J. Finn
  • Benjamin M. Hastings
  • Toby T. Hecht
  • Ira Mellman
  • Sheila A. Prindiville
  • Jaye L. Viner
  • Louis M. Weiner
  • Jason Karch
  • Thai H. Tran
  • Fransiscus E. Utama
  • Elizabeth A. Tindall
  • Ying Wang
  • Craig J. Burd
  • Eric M. Groh
  • Hoa N. Hoang
  • Graham G. Giles
  • Gianluca Severi
  • Vanessa M. Hayes
  • Brian E. Henderson
  • Loic Le Marchand
  • Laurence N. Kolonel
  • Christopher A. Haiman
  • Raffaele Baffa
  • Leonard G. Gomella
  • Erik S. Knudsen
  • Hallgeir Rui
  • Susan M. Henshall
  • Wee Ong
  • Marissa Teo
  • Victor Lee
  • Danny Ong
  • Maria G. Raso
  • Carmen Behrens
  • Matthew H. Herynk
  • Suyu Liu
  • Ludmila Prudkin
  • Natalie C. Ozburn
  • Denise M. Woods
  • Ximing Tang
  • Reza J. Mehran
  • Katia Todoerti
  • Simona Berardi
  • Addolorata Maria Luce Coluccia
  • Annunziata De Luisi
  • Michela Mattioli
  • Attilio Guarini
  • Maria Teresa Petrucci
  • Franco Dammacco
  • Domenico Ribatti
  • Antonino Neri
  • Ashley E. Galloway
  • Noriko Kawashima
چکیده

The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research. Martin A. Cheever, James P. Allison, Andrea S. Ferris, Olivera J. Finn, Benjamin M. Hastings, Toby T. Hecht, Ira Mellman, Sheila A. Prindiville, Jaye L. Viner, Louis M. Weiner, and Lynn M. Matrisian .................................................................................5323

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The prioritization of cancer antigens: a national cancer institute pilot project for the acceleration of translational research.

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The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research. Martin A. Cheever, James P. Allison, Andrea S. Ferris, Olivera J. Finn, Benjamin M. Hastings, Toby T. Hecht, Ira Mellman, Sheila A. Prindiville, Jaye L. Viner, Louis M. Weiner, and Lynn M. Matrisian ........................................................................

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The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research. Martin A. Cheever, James P. Allison, Andrea S. Ferris, Olivera J. Finn, Benjamin M. Hastings, Toby T. Hecht, Ira Mellman, Sheila A. Prindiville, Jaye L. Viner, Louis M. Weiner, and Lynn M. Matrisian ........................................................................

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Objective(s): Breast cancer is one of the most common cancers in the world and is on the increase. MUC1 and HER2 as tumor-associated antigens (TAAs) are abnormally expressed to some extent in 75–80% of breast cancers.  In our present research, a novel chimeric MUC1-HER2 (HM) protein was designed and used to study whether an immune response can be generated against these TAAs. In vitro analysis ...

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Cancer testis antigens (CTAs), a large family of tumor-associated and immunogenic antigens expressed in human tumors of various histological origins, are highly restricted to the testis and trophoblast. CTAs have been identified as potent targets for tumor-specific immunotherapeutic advances and have immensely lead to the development of different clinical trials of CTA-based vaccine therapy bec...

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تاریخ انتشار 2009